Posted by Dreamhealer in Dreamhealer, Experiments, Genetics, Healing, Naturopathic Medicine, Research, Workshops.
Tags: adam dreamhealer naturopathic, adam mcleod, adam the healer, Dreamhealer, epigenetics, naturopath
By: Dan Hurley
Your ancestors’ lousy childhoods or excellent adventures might change your personality, bequeathing anxiety or resilience by altering the epigenetic expressions of genes in the brain.
Darwin and Freud walk into a bar. Two alcoholic mice — a mother and her son — sit on two bar stools, lapping gin from two thimbles.
The mother mouse looks up and says, “Hey, geniuses, tell me how my son got into this sorry state.”
“Bad inheritance,” says Darwin.
“Bad mothering,” says Freud.
For over a hundred years, those two views — nature or nurture, biology or psychology — offered opposing explanations for how behaviors develop and persist, not only within a single individual but across generations.
And then, in 1992, two young scientists following in Freud’s and Darwin’s footsteps actually did walk into a bar. And by the time they walked out, a few beers later, they had begun to forge a revolutionary new synthesis of how life experiences could directly affect your genes — and not only your own life experiences, but those of your mother’s, grandmother’s and beyond.
The bar was in Madrid, where the Cajal Institute, Spain’s oldest academic center for the study of neurobiology, was holding an international meeting. Moshe Szyf, a molecular biologist and geneticist at McGill University in Montreal, had never studied psychology or neurology, but he had been talked into attending by a colleague who thought his work might have some application. Likewise, Michael Meaney, a McGill neurobiologist, had been talked into attending by the same colleague, who thought Meaney’s research into animal models of maternal neglect might benefit from Szyf’s perspective.
“I can still visualize the place — it was a corner bar that specialized in pizza,” Meaney says. “Moshe, being kosher, was interested in kosher calories. Beer is kosher. Moshe can drink beer anywhere. And I’m Irish. So it was perfect.”
The two engaged in animated conversation about a hot new line of research in genetics. Since the 1970s, researchers had known that the tightly wound spools of DNA inside each cell’s nucleus require something extra to tell them exactly which genes to transcribe, whether for a heart cell, a liver cell or a brain cell.
One such extra element is the methyl group, a common structural component of organic molecules. The methyl group works like a placeholder in a cookbook, attaching to the DNA within each cell to select only those recipes — er, genes — necessary for that particular cell’s proteins. Because methyl groups are attached to the genes, residing beside but separate from the double-helix DNA code, the field was dubbed epigenetics, from the prefix epi (Greek for over, outer, above).
Originally these epigenetic changes were believed to occur only during fetal development. But pioneering studies showed that molecular bric-a-brac could be added to DNA in adulthood, setting off a cascade of cellular changes resulting in cancer. Sometimes methyl groups attached to DNA thanks to changes in diet; other times, exposure to certain chemicals appeared to be the cause. Szyf showed that correcting epigenetic changes with drugs could cure certain cancers in animals.
Geneticists were especially surprised to find that epigenetic change could be passed down from parent to child, one generation after the next. A study from Randy Jirtle of Duke University showed that when female mice are fed a diet rich in methyl groups, the fur pigment of subsequent offspring is permanently altered. Without any change to DNA at all, methyl groups could be added or subtracted, and the changes were inherited much like a mutation in a gene.
Now, at the bar in Madrid, Szyf and Meaney considered a hypothesis as improbable as it was profound: If diet and chemicals can cause epigenetic changes, could certain experiences — child neglect, drug abuse or other severe stresses — also set off epigenetic changes to the DNA inside the neurons of a person’s brain? That question turned out to be the basis of a new field, behavioral epigenetics, now so vibrant it has spawned dozens of studies and suggested profound new treatments to heal the brain.
According to the new insights of behavioral epigenetics, traumatic experiences in our past, or in our recent ancestors’ past, leave molecular scars adhering to our DNA. Jews whose great-grandparents were chased from their Russian shtetls; Chinese whose grandparents lived through the ravages of the Cultural Revolution; young immigrants from Africa whose parents survived massacres; adults of every ethnicity who grew up with alcoholic or abusive parents — all carry with them more than just memories.
Like silt deposited on the cogs of a finely tuned machine after the seawater of a tsunami recedes, our experiences, and those of our forebears, are never gone, even if they have been forgotten. They become a part of us, a molecular residue holding fast to our genetic scaffolding. The DNA remains the same, but psychological and behavioral tendencies are inherited. You might have inherited not just your grandmother’s knobby knees, but also her predisposition toward depression caused by the neglect she suffered as a newborn.
Or not. If your grandmother was adopted by nurturing parents, you might be enjoying the boost she received thanks to their love and support. The mechanisms of behavioral epigenetics underlie not only deficits and weaknesses but strengths and resiliencies, too. And for those unlucky enough to descend from miserable or withholding grandparents, emerging drug treatments could reset not just mood, but the epigenetic changes themselves. Like grandmother’s vintage dress, you could wear it or have it altered. The genome has long been known as the blueprint of life, but the epigenome is life’s Etch A Sketch: Shake it hard enough, and you can wipe clean the family curse.
Twenty years after helping to set off a revolution, Meaney sits behind a wide walnut table that serves as his desk. A January storm has deposited half a foot of snow outside the picture windows lining his fourth-floor corner office at the Douglas Institute, a mental health affiliate of McGill. He has the rugged good looks and tousled salt-and-pepper hair of someone found on a ski slope — precisely where he plans to go this weekend. On the floor lays an arrangement of helium balloons in various stages of deflation. “Happy 60th!” one announces.
“I’ve always been interested in what makes people different from each other,” he says. “The way we act, the way we behave — some people are optimistic, some are pessimistic. What produces that variation? Evolution selects the variance that is most successful, but what produces the grist for the mill?”
Meaney pursued the question of individual differences by studying how the rearing habits of mother rats caused lifelong changes in their offspring. Research dating back to the 1950s had shown that rats handled by humans for as little as five to 15 minutes per day during their first three weeks of life grew up to be calmer and less reactive to stressful environments compared with their non-handled littermates. Seeking to tease out the mechanism behind such an enduring effect, Meaney and others established that the benefit was not actually conveyed by the human handling. Rather, the handling simply provoked the rats’ mothers to lick and groom their pups more, and to engage more often in a behavior called arched-back nursing, in which the mother gives the pups extra room to suckle against her underside.
“It’s all about the tactile stimulation,” Meaney says.
In a landmark 1997 paper in Science, he showed that natural variations in the amount of licking and grooming received during infancy had a direct effect on how stress hormones, including corticosterone, were expressed in adulthood. The more licking as babies, the lower the stress hormones as grown-ups. It was almost as if the mother rats were licking away at a genetic dimmer switch. What the paper didn’t explain was how such a thing could be possible.
“What we had done up to that point in time was to identify maternal care and its influence on specific genes,” Meaney says. “But epigenetics wasn’t a topic I knew very much about.”
And then he met Szyf.
“I was going to be a dentist,” Szyf says with a laugh. Slight, pale and balding, he sits in a small office at the back of his bustling laboratory — a room so Spartan, it contains just a single picture, a photograph of two embryos in a womb.
Needing to write a thesis in the late 1970s for his doctorate in dentistry at Hebrew University of Jerusalem, Szyf approached a young biochemistry professor named Aharon Razin, who had recently made a splash by publishing his first few studies in some of the world’s top scientific journals. The studies were the first to show that the action of genes could be modulated by structures called methyl groups, a subject about which Szyf knew precisely nothing. But he needed a thesis adviser, and Razin was there. Szyf found himself swept up to the forefront of the hot new field of epigenetics and never looked back.
Until researchers like Razin came along, the basic story line on how genes get transcribed in a cell was neat and simple. DNA is the master code, residing inside the nucleus of every cell; RNA transcribes the code to build whatever proteins the cell needs. Then some of Razin’s colleagues showed that methyl groups could attach to cytosine, one of the chemical bases in DNA and RNA.
It was Razin, working with fellow biochemist Howard Cedar, who showed these attachments weren’t just brief, meaningless affairs. The methyl groups could become married permanently to the DNA, getting replicated right along with it through a hundred generations. As in any good marriage, moreover, the attachment of the methyl groups significantly altered the behavior of whichever gene they wed, inhibiting its transcription, much like a jealous spouse. It did so, Razin and Cedar showed, by tightening the thread of DNA as it wrapped around a molecular spool, called a histone, inside the nucleus. The tighter it is wrapped, the harder to produce proteins from the gene.
Consider what that means: Without a mutation to the DNA code itself, the attached methyl groups cause long-term, heritable change in gene function. Other molecules, called acetyl groups, were found to play the opposite role, unwinding DNA around the histone spool, and so making it easier for RNA to transcribe a given gene.
By the time Szyf arrived at McGill in the late 1980s, he had become an expert in the mechanics of epigenetic change. But until meeting Meaney, he had never heard anyone suggest that such changes could occur in the brain, simply due to maternal care.
“It sounded like voodoo at first,” Szyf admits. “For a molecular biologist, anything that didn’t have a clear molecular pathway was not serious science. But the longer we talked, the more I realized that maternal care just might be capable of causing changes in DNA methylation, as crazy as that sounded. So Michael and I decided we’d have to do the experiment to find out.”
Actually, they ended up doing a series of elaborate experiments. With the assistance of postdoctoral researchers, they began by selecting mother rats who were either highly attentive or highly inattentive. Once a pup had grown up into adulthood, the team examined its hippocampus, a brain region essential for regulating the stress response. In the pups of inattentive mothers, they found that genes regulating the production of glucocorticoid receptors, which regulate sensitivity to stress hormones, were highly methylated; in the pups of conscientious moms, the genes for the glucocorticoid receptors were rarely methylated.
Methylation just gums up the works. So the less the better when it comes to transcribing the affected gene. In this case, methylation associated with miserable mothering prevented the normal number of glucocorticoid receptors from being transcribed in the baby’s hippocampus. And so for want of sufficient glucocorticoid receptors, the rats grew up to be nervous wrecks.
To demonstrate that the effects were purely due to the mother’s behavior and not her genes, Meaney and colleagues performed a second experiment. They took rat pups born to inattentive mothers and gave them to attentive ones, and vice versa. As they predicted, the rats born to attentive mothers but raised by inattentive ones grew up to have low levels of glucocorticoid receptors in their hippocampus and behaved skittishly. Likewise, those born to bad mothers but raised by good ones grew up to be calm and brave and had high levels of glucocorticoid receptors.
Before publishing their findings, Meaney and Szyf conducted a third crucial experiment, hoping to overwhelm the inevitable skeptics who would rise up to question their results. After all, it could be argued, what if the epigenetic changes observed in the rats’ brains were not directly causing the behavioral changes in the adults, but were merely co-occurring? Freud certainly knew the enduring power of bad mothers to screw up people’s lives. Maybe the emotional effects were unrelated to the epigenetic change.
To test that possibility, Meaney and Szyf took yet another litter of rats raised by rotten mothers. This time, after the usual damage had been done, they infused their brains with trichostatin A, a drug that can remove methyl groups. These animals showed none of the behavioral deficits usually seen in such offspring, and their brains showed none of the epigenetic changes.
“It was crazy to think that injecting it straight into the brain would work,” says Szyf. “But it did. It was like rebooting a computer.”
Despite such seemingly overwhelming evidence, when the pair wrote it all up in a paper, one of the reviewers at a top science journal refused to believe it, stating he had never before seen evidence that a mother’s behavior could cause epigenetic change.
“Of course he hadn’t,” Szyf says. “We wouldn’t have bothered to report the study if it had already been proved.”
In the end, their landmark paper, “Epigenetic programming by maternal behavior,” was published in June 2004 in the journal Nature Neuroscience.
Meaney and Szyf had proved something incredible. Call it postnatal inheritance: With no changes to their genetic code, the baby rats nonetheless gained genetic attachments due solely to their upbringing — epigenetic additions of methyl groups sticking like umbrellas out the elevator doors of their histones, gumming up the works and altering the function of the brain.
The Beat Goes On
Together, Meaney and Szyf have gone on to publish some two-dozen papers, finding evidence along the way of epigenetic changes to many other genes active in the brain. Perhaps most significantly, in a study led by Frances Champagne — then a graduate student in Meaney’s lab, now an associate professor with her own lab at Columbia University in New York — they found that inattentive mothering in rodents causes methylation of the genes for estrogen receptors in the brain. When those babies grow up, the resulting decrease of estrogen receptors makes them less attentive to their babies. And so the beat goes on.
As animal experiments continue apace, Szyf and Meaney have entered into the next great step in the study of behavioral epigenetics: human studies. In a 2008 paper, they compared the brains of people who had committed suicide with the brains of people who had died suddenly of factors other than suicide. They found excess methylation of genes in the suicide brains’ hippocampus, a region critical to memory acquisition and stress response. If the suicide victims had been abused as children, they found, their brains were more methylated.
Why can’t your friend “just get over” her upbringing by an angry, distant mother? Why can’t she “just snap out of it”? The reason may well be due to methyl groups that were added in childhood to genes in her brain, thereby handcuffing her mood to feelings of fear and despair.
Of course, it is generally not possible to sample the brains of living people. But examining blood samples in humans is routine, and Szyf has gone searching there for markers of epigenetic methylation. Sure enough, in 2011 he reported on a genome-wide analysis of blood samples taken from 40 men who participated in a British study of people born in England in 1958.
All the men had been at a socioeconomic extreme, either very rich or very poor, at some point in their lives ranging from early childhood to mid-adulthood. In all, Szyf analyzed the methylation state of about 20,000 genes. Of these, 6,176 genes varied significantly based on poverty or wealth. Most striking, however, was the finding that genes were more than twice as likely to show methylation changes based on family income during early childhood versus economic status as adults.
Timing, in other words, matters. Your parents winning the lottery or going bankrupt when you’re 2 years old will likely affect the epigenome of your brain, and your resulting emotional tendencies, far more strongly than whatever fortune finds you in middle age.
Last year, Szyf and researchers from Yale University published another study of human blood samples, comparing 14 children raised in Russian orphanages with 14 other Russian children raised by their biological parents. They found far more methylation in the orphans’ genes, including many that play an important role in neural communication and brain development and function.
“Our study shows that the early stress of separation from a biological parent impacts long-term programming of genome function; this might explain why adopted children may be particularly vulnerable to harsh parenting in terms of their physical and mental health,” said Szyf’s co-author, psychologist Elena Grigorenko of the Child Study Center at Yale. “Parenting adopted children might require much more nurturing care to reverse these changes in genome regulation.”
A case study in the epigenetic effects of upbringing in humans can be seen in the life of Szyf’s and Meaney’s onetime collaborator, Frances Champagne. “My mom studied prolactin, a hormone involved in maternal behavior. She was a driving force in encouraging me to go into science,” she recalls. Now a leading figure in the study of maternal influence, Champagne just had her first child, a daughter. And epigenetic research has taught her something not found in the What to Expect books or even her mother’s former lab.
“The thing I’ve gained from the work I do is that stress is a big suppressor of maternal behavior,” she says. “We see it in the animal studies, and it’s true in humans. So the best thing you can do is not to worry all the time about whether you’re doing the right thing. Keeping the stress level down is the most important thing. And tactile interaction — that’s certainly what the good mother rats are doing with their babies. That sensory input, the touching, is so important for the developing brain.”
The Mark Of Cain
The message that a mother’s love can make all the difference in a child’s life is nothing new. But the ability of epigenetic change to persist across generations remains the subject of debate. Is methylation transmitted directly through the fertilized egg, or is each infant born pure, a methylated virgin, with the attachments of methyl groups slathered on solely by parents after birth?
Neuroscientist Eric Nestler of the Icahn School of Medicine at Mount Sinai in New York has been seeking an answer for years. In one study, he exposed male mice to 10 days of bullying by larger, more aggressive mice. At the end of the experiment, the bullied mice were socially withdrawn.
To test whether such effects could be transmitted to the next generation, Nestler took another group of bullied mice and bred them with females, but kept them from ever meeting their offspring.
Despite having no contact with their depressed fathers, the offspring grew up to be hypersensitive to stress. “It was not a subtle effect; the offspring were dramatically more susceptible to developing signs of depression,” he says.
In further testing, Nestler took sperm from defeated males and impregnated females through in vitro fertilization. The offspring did not show most of the behavioral abnormalities, suggesting that epigenetic transmission may not be at the root. Instead, Nestler proposes, “the female might know she had sex with a loser. She knows it’s a tainted male she had sex with, so she cares for her pups differently,” accounting for the results.
Despite his findings, no consensus has yet emerged. The latest evidence, published in the Jan. 25 issue of the journal Science, suggests that epigenetic changes in mice are usually erased, but not always. The erasure is imperfect, and sometimes the affected genes may make it through to the next generation, setting the stage for transmission of the altered traits in descendants as well.
The studies keep piling on. One line of research traces memory loss in old age to epigenetic alterations in brain neurons. Another connects post-traumatic stress disorder to methylation of the gene coding for neurotrophic factor, a protein that regulates the growth of neurons in the brain.
If it is true that epigenetic changes to genes active in certain regions of the brain underlie our emotional and intellectual intelligence — our tendency to be calm or fearful, our ability to learn or to forget — then the question arises: Why can’t we just take a drug to rinse away the unwanted methyl groups like a bar of epigenetic Irish Spring?
The hunt is on. Giant pharmaceutical and smaller biotech firms are searching for epigenetic compounds to boost learning and memory. It has been lost on no one that epigenetic medications might succeed in treating depression, anxiety and post-traumatic stress disorder where today’s psychiatric drugs have failed.
But it is going to be a leap. How could we be sure that epigenetic drugs would scrub clean only the dangerous marks, leaving beneficial — perhaps essential — methyl groups intact? And what if we could create a pill potent enough to wipe clean the epigenetic slate of all that history wrote? If such a pill could free the genes within your brain of the epigenetic detritus left by all the wars, the rapes, the abandonments and cheated childhoods of your ancestors, would you take it?
Retrieved from: http://discovermagazine.com/2013/may/13-grandmas-experiences-leave-epigenetic-mark-on-your-genes#.UxPna_RdXWo
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Posted by Dreamhealer in Alternative medicine, Breast Cancer, Cancer, Diet, Dreamhealer, Energy Healing, Health, Integrative Medicine, Naturopathic Medicine, Press, Research, Skeptics.
Tags: adam dreamhealer, adam mcleod, breast cancer, Cancer, dream healer, Dreamhealer, Naturopathic doctor, naturopathy
By: Charles J Wright
When first introduced four decades ago, breast cancer screening with mammography was widely regarded as an important tool in the fight against a terrible disease. It seemed obvious that the earlier it could be diagnosed the more lives could be saved. Aggressive treatment, it was thought, would prevent the cancer from spreading through the body. A huge amount of research evidence since then has slowly and painfully led to a different conclusion.
It is now clear that the benefits of screening mammography have been greatly exaggerated and the serious adverse effects all but ignored in the enthusiasm to support breast screening programs. It’s time for these programs to be reconsidered.
It must be emphasized that this is the case for population screening of healthy women, not those with extra high risk factors.
This is a very unpleasant message for modern developed societies where three generations of women have been led to believe that regular mammograms will save their lives and where an enormous related industry has been built up, but it is time to face the facts.
Unscientific opinions and powerful vested interests abound on this subject, so it is essential to focus on well-conducted studies from independent sources to summarize the evidence. One of the most trusted of these, the Cochrane Collaboration, has been studying screening mammography intensively. Its most recent bulletin states that the benefit of screening 2,000 women regularly for 10 years is that one woman may have her life prolonged. Of the other 1,999 women, at least 200 will have false positive mammograms leading to biopsies and surgery, and at least 10 women will be falsely diagnosed with breast cancer and consequently subjected to unnecessary surgery, radiotherapy and chemotherapy.
This problem, called over-diagnosis, occurs when a biopsy reveals microscopic cells that are currently labeled as “cancer” by the pathologist, but with uncertain potential to cause any significant problem for the patient in the future. The “c” word inevitably causes fear and distress for the patient and an aggressive treatment plan from the doctors. This is now widely recognized, even by the U.S. National Cancer Institute which has recently recommended that these uncertain “cancers” should instead be labeled “IDLE” (indolent lesions) until research can help us differentiate those that need treatment from those that do not.
Now we have more evidence. The Canadian National Breast Cancer Screening Study published this week in the British Medical Journal, and widely reported in the international media, solidly confirms that there is no upside to breast screening healthy women in terms of mortality benefit in exchange for the downside of all the adverse consequences. In this study, 90,000 women aged 40-59 were randomly allocated to the mammography screening program or to annual physical examination only, with follow up to 25 years. The mortality was the same in both groups (500 in the first group and 505 in the second).
Adverse consequences from screening can include false negatives (a cancer is growing but missed by the mammogram), and potentially cancer-causing cumulative X-ray exposure. Not to mention the anxiety, pain and discomfort that women experience with the procedure and the huge cost of these programs to the health care system.
This new study, along with the Cochrane analysis, represent the beginning of a growing consensus among scientists and clinical epidemiologists that the evidence no longer supports population screening of healthy women with mammography. Several prominent female U.K. doctors have gone public about choosing not to have breast cancer screening, including the editor of the BMJ, the past president of the Royal College of GPs, and the professor of obstetrics at King’s College London.
Nobody can be happy about all of this disappointing news with its serious public, professional and political implications, but surely we cannot ignore it. The hope that breast screening could cause a reduction in the mortality from this terrible disease was at first well placed 40 years ago, but it is no longer possible to advocate for an intervention that carries such a tiny (if any) likelihood of benefit along with such a huge burden of harmful consequences.
The very essence of science is about seeking truth through the constant cycle of evidence, analysis and revision. In response to a hostile question, John Maynard Keynes famously remarked “When the facts change, I change my mind. What do you do, sir?” We should heed that lesson here.
It may take a long time to dispel the false hope that has been given to women with mammogram screening, but the very least and immediate response should be the development of a mandatory consent form for women to sign before screening that distinguishes the most recent and overwhelming evidence from the current inappropriate enthusiasm. Women would then be empowered to make an informed choice.
Public health agencies should also consider a comprehensive plan for public re-education about screening mammography, followed by the gradual dismantling of population breast screening programs across the country.
Retrieved from: http://www.theglobeandmail.com/globe-debate/now-that-we-know-mammograms-are-flawed-its-time-to-change-course/article16847982/
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Posted by Dreamhealer in Alternative medicine, Dreamhealer, Energy Healing, Healing, Health, Workshops.
Tags: adam dream healer, adam the healer, alternative healing, Alternative medicine, Dreamhealer, dreamhealer workshop, Energy Healing
Adam Dreamhealer holds ‘Integrative Healing workshops‘ around the world promoting what he sees as the most overlooked aspect in preventative health care today: involving the patient in their own health care by using their focused healing intentions. At his workshop events, participants experience self-empowerment as Adam merges the auras of all present and performs two unique group energy treatments. He gives everyone present, the tools to activate their own innate healing power. Forty percent of those who attend Adam’s one-day workshops are healthcare professionals learning how to integrate Adam’s techniques into their practices. Rolling Stone Magazine calls Adam “One of the world’s most in-demand healers”.
Adam Dreamhealer is a graduate in Molecular Biology and biochemistry, healer, best-selling author, speaker and teacher of self-empowerment. It is well known that a positive attitude promotes healing. This knowledge is a basic survival instinct and just needs to be activated in order to maximize its effect. From a very young age it is accepted that intention is an important factor in any healing process. Medical communities in cultures all around the world have known for thousands of years that a focused positive patient is more likely to heal. Adam Dreamhealer emphasizes this at each of his workshops, in his books and DVD as the most powerful, yet overlooked preventative aspect of medicine.
In the 1950′s when Watson and Crick solved the structure of DNA things suddenly changed. The scientific community became obsessed with finding a structural biochemical explanation for every biological event. As technology advanced it seemed that every mystery in biology could be explained by physical chemical interactions. In 2003 the human genome was sequenced and at that time this was thought to be the final frontier in molecular biology, which would leave few remaining mysteries in biology.
Rather than solving all biological questions, it was realized that there are many important mechanisms that are poorly understood. Stem cells are particularly effective at highlighting some key concepts that remain unknown. Every cell in a person’s body carries the exact same genetic information, yet the brain cells look and function dramatically different than skin cells. How is this possible?
It turns out that there are proteins that associate with the DNA and it is these proteins that determine which genes are “turned on” and which ones are not. It is this selective control of the DNA that results in these cells having completely different properties. These discoveries resulted in the development of a new field of study known as epigenetics. This has dramatically changed our understanding of biology as epigenetics established that environment has a significant and detectable impact on changes in every cell in the body, and every protein.
With regards to healing this is important because proteins are incredibly sensitive to their environment. The slightest change in the environment results in significant changes to these proteins, which consequently influence every aspect of the cell metabolism. When someone is trying to improve his or her health, regardless of what the medical condition is, the goal is to change cell metabolism such that balance can once again be restored.
A crucial factor in the environment is how a person chooses to perceive their environment. It is certainly evident that the human body reacts differently when relaxed as opposed to when stressed or tensed. If a situation is perceived to be positive and ideal for healing then this changes the environment within the body. This directly influences cellular events and consequently health.
Human cells are no longer considered to be complex biochemical machines that function solely on chemical and physical interactions. It is important to remember that cells are conscious organisms that do everything possible to maximize their contribution to health and wellbeing. Every cell in the body is functioning together for the benefit of the whole organism. This knowledge is very empowering because everyone has the power to influence every biochemical event that occurs in the body.
Finally molecular biology is beginning to confirm what has been known to be true for thousands of years, that our intentions influence our health. So take the time to clear your mind and talk with your cells because they are certainly listening to what you have to say.
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Integrative Healing Workshop – Seattle, WA- March 8, 2014
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Integrative Healing Workshop -Calgary, Alberta – September 20, 2014
Integrative Healing Workshop -Vancouver, British Columbia – October 5, 2014
Posted by Dreamhealer in Alternative medicine, Big Pharma, Colds, Diet, Dreamhealer, Healing, Health, Healthcare, Naturopathic Medicine, Naturopathy, Research, vitamins.
Tags: Alternative medicine, flu, flu prevention, flu season, flu shot, Influenza, research
By: Dr. Frank Lipman
While it’s become popular in the last decade to rely on vaccines to protect us from the flu, there are a number of problems with this that are rarely discussed. First is the fact that the effectiveness of flu shots has yet to be proven. In fact, many studies show that getting vaccinated has no impact on the likelihood of catching the flu for babies, adults, or the elderly.
Then there’s the question of the toxic ingredients used to manufacture flu vaccines – and it’s not mandatory to disclose such ingredients to recipients of the vaccines. While this entertaining video pokes fun at the topic, it’s definitely worth considering whether you’re willing to inject substances like mercury and formaldehyde into your body, especially for a practice with unproven results.
You may be wondering how such a highly recommended “solution” could be so ineffective. The answer lies in the biology of the flu virus. Vaccines are made from disabled strains of the flu from past seasons, which trick the body into producing antibodies to fight against them.
Ideally, the body should then be better able to defend against the virus if/when it encounters the same strain again. However, the reality is that flu viruses mutate very quickly, so the strain you encounter mid-season may be unrecognized as the strain you were vaccinated against, or worse it may have adapted into a strain that is more resistant than the version you were vaccinated against.
Either way, the result of the vaccine is rendered useless, and your body is likely to succumb to the virus. Luckily, there are lots of ways to protect yourself from the flu without relying on a flu shot.
Here are my top 5 super simple recommendations:
1. Stock up on Vitamin D.
Vitamin D is an essential nutrient that keeps the body functioning optimally, and especially supports the immune system. Some studies have shown it to be a flu fighter. Interestingly, flu season corresponds with winter – the time of year when we are least able to take in adequate levels of Vitamin D from the primary source: sunshine! I recommend having your Vitamin D checked and ideally, you want your level between 50 and 80 ng/ml. Your best bet is probably to take a Vitamin D3 supplement daily.
2. Take a probiotic every day.
A strong immune system relies heavily on having a healthy, well-functioning gut (as 70% of your immune system is in the gut), and probiotics help keep your gut engine humming. Look for a probiotic with at least 10-20 billion organisms and take daily.
3. Avoid sugar, gluten, and processed foods.
These dramatically decrease immune function. Instead load up on nutrient-rich whole foods. Start your day with a smoothie full of goodness in the form of healthy fats (almond or coconut milk, avocado, almond butter), some frozen berries, chia seeds and a good protein powder. Lunches and dinners of nourishing soups, colorful salads, and dark greens and veggies are packed with flu-fighting phytonutrients.
4. Give your body an easy antiviral boost.
Antiviral herbs boost your immunity and help protect you without creating resistant viral strains. Four great antivirals are
- Olive leaf extract
- Grapefruit seed extract
- Elderberry extract
You can also dig into garlic, which has antiviral properties and is a known immunity booster.
5. Don’t skimp on sleep.
Getting enough sleep is a key component to a flu-free winter! There’s no better time for the body to restore and repair itself than while you rest. Shoot for at least 7 hours a night and try taking a 20-minute power nap if you’re falling short. If sleep is not your strong suit, check out my top tips for improving your sleep.
Reducing stress is particularly important during flu season. Exercise helps to keep your immune system healthy, but don’t overdo it – your workout shouldn’t be a stress to your body! Light strength training, breathing exercises, yoga, or simply taking the time for things you enjoy will relieve tension and enhance physical and mental resilience.
7. Lay off the antibacterial soap & hand sanitizers.
The antibacterial craze has created harsh products loaded with toxins that increase the risk of creating resistant bacteria. They also over-dry and crack the skin, making transmission of viruses that much easier. Instead, wash your hands frequently with good, old-fashioned hot water and chemical-free soap. When you feel the need for an on-the-spot cleaning, try a few drops of lavender essential oil for a natural hand sanitizer.
With these tips, staying flu-free this winter should be a breeze.
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Posted by Dreamhealer in Alternative medicine, Dreamhealer, Energy Healing, Experiments, Genetics, Healing, Integrative Medicine, Meditation, Naturopathic Medicine, Spirituality.
Tags: adam dreamhealer, dr dreamhealer, Dreamhealer, dreamhealer blog, Energy Healing, healing with intention, intention healing
By: Michael Forrester
With evidence growing that training the mind or inducing certain modes of consciousness can have positive health effects, researchers have sought to understand how these practices physically affect the body. A new study by researchers in Wisconsin, Spain, and France reports the first evidence of specific molecular changes in the body following a period of intensive mindfulness practice.
The study investigated the effects of a day of intensive mindfulness practice in a group of experienced meditators, compared to a group of untrained control subjects who engaged in quiet non-meditative activities. After eight hours of mindfulness practice, the meditators showed a range of genetic and molecular differences, including altered levels of gene-regulating machinery and reduced levels of pro-inflammatory genes, which in turn correlated with faster physical recovery from a stressful situation.
“To the best of our knowledge, this is the first paper that shows rapid alterations in gene expression within subjects associated with mindfulness meditation practice,” says study author Richard J. Davidson, founder of the Center for Investigating Healthy Minds and the William James and Vilas Professor of Psychology and Psychiatry at the University of Wisconsin-Madison.
“Most interestingly, the changes were observed in genes that are the current targets of anti-inflammatory and analgesic drugs,” says Perla Kaliman, first author of the article and a researcher at the Institute of Biomedical Research of Barcelona, Spain (IIBB-CSIC-IDIBAPS), where the molecular analyses were conducted.
The study was published in the Journal Psychoneuroendocrinology.
Mindfulness-based trainings have shown beneficial effects on inflammatory disorders in prior clinical studies and are endorsed by the American Heart Association as a preventative intervention. The new results provide a possible biological mechanism for therapeutic effects.
Gene Activity Can Change According To Perception
According to Dr. Bruce Lipton, gene activity can change on a daily basis. If the perception in your mind is reflected in the chemistry of your body, and if your nervous system reads and interprets the environment and then controls the blood’s chemistry, then you can literally change the fate of your cells by altering your thoughts.
In fact, Dr. Lipton’s research illustrates that by changing your perception, your mind can alter the activity of your genes and create over thirty thousand variations of products from each gene. He gives more detail by saying that the gene programs are contained within the nucleus of the cell, and you can rewrite those genetic programs through changing your blood chemistry.
In the simplest terms, this means that we need to change the way we think if we are to heal cancer. “The function of the mind is to create coherence between our beliefs and the reality we experience,” Dr. Lipton said. “What that means is that your mind will adjust the body’s biology and behavior to fit with your beliefs. If you’ve been told you’ll die in six months and your mind believes it, you most likely will die in six months. That’s called the nocebo effect, the result of a negative thought, which is the opposite of the placebo effect, where healing is mediated by a positive thought.”
That dynamic points to a three-party system: there’s the part of you that swears it doesn’t want to die (the conscious mind), trumped by the part that believes you will (the doctor’s prognosis mediated by the subconscious mind), which then throws into gear the chemical reaction (mediated by the brain’s chemistry) to make sure the body conforms to the dominant belief. (Neuroscience has recognized that the subconscious controls 95 percent of our lives.)
Now what about the part that doesn’t want to die–the conscious mind? Isn’t it impacting the body’s chemistry as well? Dr. Lipton said that it comes down to how the subconscious mind, which contains our deepest beliefs, has been programmed. It is these beliefs that ultimately cast the deciding vote.
“It’s a complex situation,” said Dr. Lipton. People have been programmed to believe that they’re victims and that they have no control. We’re programmed from the start with our mother and father’s beliefs. So, for instance, when we got sick, we were told by our parents that we had to go to the doctor because the doctor is the authority concerning our health. We all got the message throughout childhood that doctors were the authority on health and that we were victims of bodily forces beyond our ability to control. The joke, however, is that people often get better while on the way to the doctor. That’s when the innate ability for self-healing kicks in, another example of the placebo effect.
Mindfulness Practice Specifically Affects Regulatory Pathways
The results of Davidson’s study show a down-regulation of genes that have been implicated in inflammation. The affected genes include the pro-inflammatory genes RIPK2 and COX2 as well as several histone deacetylase (HDAC) genes, which regulate the activity of other genes epigenetically by removing a type of chemical tag. What’s more, the extent to which some of those genes were downregulated was associated with faster cortisol recovery to a social stress test involving an impromptu speech and tasks requiring mental calculations performed in front of an audience and video camera.
Biologists have suspected for years that some kind of epigenetic inheritance occurs at the cellular level. The different kinds of cells in our bodies provide an example. Skin cells and brain cells have different forms and functions, despite having exactly the same DNA. There must be mechanisms–other than DNA–that make sure skin cells stay skin cells when they divide.
Perhaps surprisingly, the researchers say, there was no difference in the tested genes between the two groups of people at the start of the study. The observed effects were seen only in the meditators following mindfulness practice. In addition, several other DNA-modifying genes showed no differences between groups, suggesting that the mindfulness practice specifically affected certain regulatory pathways.
The key result is that meditators experienced genetic changes following mindfulness practice that were not seen in the non-meditating group after other quiet activities — an outcome providing proof of principle that mindfulness practice can lead to epigenetic alterations of the genome.
Previous studies in rodents and in people have shown dynamic epigenetic responses to physical stimuli such as stress, diet, or exercise within just a few hours.
“Our genes are quite dynamic in their expression and these results suggest that the calmness of our mind can actually have a potential influence on their expression,” Davidson says.
“The regulation of HDACs and inflammatory pathways may represent some of the mechanisms underlying the therapeutic potential of mindfulness-based interventions,” Kaliman says. “Our findings set the foundation for future studies to further assess meditation strategies for the treatment of chronic inflammatory conditions.”
Subconscious Beliefs Are Key
Too many positive thinkers know that thinking good thoughts–and reciting affirmations for hours on end–doesn’t always bring about the results that feel-good books promise.
Dr. Lipton didn’t argue this point, because positive thoughts come from the conscious mind, while contradictory negative thoughts are usually programmed in the more powerful subconscious mind.
“The major problem is that people are aware of their conscious beliefs and behaviors, but not of subconscious beliefs and behaviors. Most people don’t even acknowledge that their subconscious mind is at play, when the fact is that the subconscious mind is a million times more powerful than the conscious mind and that we operate 95 to 99 percent of our lives from subconscious programs.
“Your subconscious beliefs are working either for you or against you, but the truth is that you are not controlling your life, because your subconscious mind supersedes all conscious control. So when you are trying to heal from a conscious level–citing affirmations and telling yourself you’re healthy–there may be an invisible subconscious program that’s sabotaging you.”
The power of the subconscious mind is elegantly revealed in people expressing multiple personalities. While occupying the mind-set of one personality, the individual may be severely allergic to strawberries. Then, in experiencing the mind-set of another personality, he or she eats them without consequence.
The new science of epigenetics promises that every person on the planet has the opportunity to become who they really are, complete with unimaginable power and the ability to operate from, and go for, the highest possibilities, including healing our bodies and our culture and living in peace.
Read more http://www.tunedbody.com/scientists-finally-show-thoughts-can-cause-specific-molecular-changes-genes/#
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Posted by Dreamhealer in Alternative medicine, Dreamhealer, Emotion, Experiments, Health, Integrative Medicine, Naturopathic Medicine, Research.
Next time you’ve got a public speaking engagement or exam coming up, psych yourself up by telling yourself how excited you are rather than trying to calm down and you may actually perform better.
That’s according to a new Harvard study published by the American Psychological Association, which found that affirmative statements like “I’m excited” helped people improve their performance compared to self-pep talks that urged relaxation such as “I am calm.”
“People have a very strong intuition that trying to calm down is the best way to cope with their anxiety, but that can be very difficult and ineffective,” said study author Alison Wood Brooks in a statement.
“When people feel anxious and try to calm down, they are thinking about all the things that could go badly. When they are excited, they are thinking about how things could go well.”
The results of the study are based on several different experiments. In one experiment, 140 participants were instructed to prepare a public speech on why they would be good work partners. Researchers videotaped the speeches and participants were told they would be judged by a committee to increase anxiety levels.
Before delivering their spiel, subjects were instructed to say either “I am excited” or “I am calm.” Judges found that those who made the first statement were more persuasive, competent and relaxed, the study says.
Similar results were observed during a math exam, with those who psyched themselves up with the mantra “I am excited” scoring an impressive eight percent higher on average compared to the “I am calm” and control groups.
In a karaoke experiment in which participants’ heart rates were monitored with a pulse meter, again singers who repeated the mantra “I am excited” scored an average of 80 percent on the karaoke machine which measures pitch, rhythm and volume. Those instructed to tell themselves they were calm, angry or sad scored 69 percent.
The moral of the study?
“It really does pay to be positive, and people should say they are excited. Even if they don’t believe it at first, saying ‘I’m excited’ out loud increases authentic feelings of excitement,” Brooks said.
A 2012 study out of the University of Chicago also found that performing math equations under anxiety prompts responses in the brain similar to physical pain.
Read more: http://www.ctvnews.ca/health/body-and-mind/improve-your-performance-with-this-mantra-i-am-excited-1.1608359#ixzz2ohpOvCB5
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Posted by Dreamhealer in Healing.
Tags: Corruption, Drugs, Health, Healthcare, Pharma
Fascinating interview with Peter Gøtzsche on the topic of his recently-released book “Deadly Medicines and Organized Crime: How Big Pharma has Corrupted Healthcare” as featured on MadInAmerica.com.
“My studies in this area lead me to a very uncomfortable conclusion: Our citizens would be far better off if we removed all the psychotropic drugs from the market, as doctors are unable to handle them. It is inescapable that their availability creates more harm than good.”
- Peter Gøtzsche, MD; Co-founder of the Cochrane Collaboration
Posted by Dreamhealer in Alternative medicine, Big Pharma, Cancer, Cardiovascular disease, Diet, Dreamhealer, Experiments, Government, Health, Integrative Medicine, Naturopathic Medicine.
Tags: adam mcleod, dream healer, Dreamhealer, Energy Healing
By: Hank Schultz
The Congressional Dietary Supplement Caucus in conjunction with the leading dietary supplement industry associations held a briefing yesterday for members of Congress to drive home the point that supplements are not only good for users’ health, but good for the nation’s health care bottom line, too.
The briefing, titled “Smart Prevention: Health Care Cost Savings Utilizing Dietary Supplements,” was held by the DSC and the American Herbal Products Association (AHPA), the Consumer Healthcare Products Association (CHPA), the Council for Responsible Nutrition (CRN), the Natural Products Association (NPA), and the United Natural Products Alliance (UNPA).
The message given to Congressional staffs was backed by data gather in the recent Frost and Sullivan survey commissioned by the CRN Foundation that showed that demonstrated that supplementation at preventive intake levels in high-risk populations can reduce the number of medical events associated with heart disease, age-related eye disease, diabetes, and bone disease in the United States, representing the potential for significant cost savings.
Mike Greene, the vice president of government relations for CRN, said the message seemed to get through. Such briefings tend to be high traffic affairs, with Congressional staffers coming and going as competing needs arise for their time.
“Typically staff members are very busy. I was interested in the simple fact that people stayed. We weren’t talking about the health benefits of dietary supplements, but we were talking about the economic benefits of dietary supplements,”Green told NutraIngredients-USA.
Part of the meeting consisted of a presentation of the report’s findings by Steve Mister, president and CEO of CRN, and included a statement by John Shaw, executive director of NPA.
“Chronic diseases are one of the greatest contributors to health care costs in this country,” said Mister. “If we can identify and motivate those at risk to effectively use dietary supplements, we can control rising societal health care costs, but also give sick individuals a chance to reduce the risk of costly events and, most importantly, to improve their quality of life.”
The new report by economic firm Frost & Sullivan that examined four different chronic diseases and the potential for health care cost savings when U.S. adults, 55 and older, diagnosed with these chronic diseases, used one of eight different dietary supplement regimens.
The report, performed a systematic review of hundreds of scientific studies on eight dietary supplement regimens across four diseases to determine the reduction in disease risk from these preventive practices. The firm then projected the rates of medical events across the high-risk populations and applied cost benefit analyses to determine the cost savings if people at high risk took supplements at preventive intake levels.
The report, demonstrated that supplementation at preventive intake levels in high-risk populations can reduce the number of medical events associated with heart disease, age-related eye disease, diabetes, and bone disease in the United States, representing the potential for significant cost savings. Calculated potential savings in health care costs ranged as high as $3.9 billion for omega-3 supplements in the reduction of significant cardiac disease events.
“Nutritional supplements proactively contribute to the overall health and well-being of American consumers. But as we can see from this data, the benefits of supplementation are much more far-reaching,” Shaw said.
“I’ve always known that dietary supplements have benefits. Most people know that. But by doing this report we’ve shown that dietary supplements can reduce health care costs as well. This information is new and its fresh and it’s interesting to see how it has been received,” Greene said.
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Posted by Dreamhealer in ADHD, Allergies, Alternative medicine, Antibiotics, Experiments, Genetics, Healing, Health, naturopathic, Naturopathic Medicine, Naturopathy, Research.
Tags: adam mcleod, autisum, Dreamhealer, healer, naturopathic
By: Emily Underwood
Many physicians and parents report that their autistic children have unusually severe gastrointestinal problems, such as chronic constipation or diarrhea. These observations have led some researchers to speculate that an ailing gut contributes to the disorder in some cases, but scientific data has been lacking. Now, a provocative study claims that a probiotic treatment for gastrointestinal issues can reduce autismlike symptoms in mice and suggests that this treatment could work for humans, too.
The reported incidence of gut maladies in people with autism varies wildly between published studies—from zero to more than 80%—making it difficult to establish just how commonly the two conditions go together, says principal investigator Sarkis Mazmanian, a microbiologist at the California Institute of Technology (Caltech) in Pasadena. Overall, however, the evidence seems to point toward a connection. Last year, for example, a Centers for Disease Control and Prevention study of thousands of children with developmental disabilities found that kids with autism were twice as likely as children with other types of disorders to have frequent diarrhea or colitis, an inflammation of the large intestine.
For many years, Mazmanian and his and colleagues have been studying the effects of a nontoxic strain of the bacterium Bacteroides fragilis on diseases such as Crohn’s disease, which causes intestinal inflammation and allows potentially harmful substances that should pass out of the body to leak through junctions between cells that are normally tight. Although the researchers don’t understand the mechanism, the bacterium appears to restore the damaged gut, possibly by helping close these gaps.
“The fact that we have an organism that repairs the gut makes it a very appealing” tool for testing whether gut abnormalities can contribute to autism, Mazmanian says. To explore that question, Mazmanian and colleagues at Caltech used a mouse model of autism that is thought to approximately recreate three of the disorder’s hallmark deficits: lack of social interaction, decreased communication (mice normally emit ultrasonic, birdsonglike chirps), and repetitive behaviors such as compulsive grooming or burying marbles.
The first step of the experiment was to determine whether the mice showed signs of gastrointestinal inflammation or other gut abnormalities, says microbiologist Elaine Hsiao, a postdoctoral candidate at Caltech and lead author of the study. By the time the mice were 3 weeks old, the researchers found that their intestines were indeed as leaky as those of mice that had been treated with a chemical that induces colitis. Next, the researchers tested whether they could reverse the damage by feeding the mice applesauce laced with B. fragilis for a week. A second group of autism-mimicking mice as well as a group of healthy mice ate applesauce that did not contain the bacteria. Then the group waited to see what effect the bacteria would have on the rodents’ intestines. “We didn’t know what would happen—we were hoping the bacterium would survive in the gut,” Hsiao says.
After 3 weeks, the team measured the levels of gut-derived molecules in the rodents’ bloodstream and found that the treatment had stopped up their intestinal leakage. Bacterial counts from rodents’ poop showed that although B. fragilis did not establish lasting colonies in the mice, they did “shake up the community,” of microorganisms, bringing it closer to that of the normal mice, Hsiao says. After the treatment, the autism-mimicking mice also resembled their normal peers in two behavioral tests, the authors report today in Cell. The animals no longer compulsively buried marbles in their cages and increased their ultrasonic squeaking to typical levels. They did not increase their social interactions, however, Hsiao says.
“It’s really striking that any bacterial treatment—even a transient one—could have a lasting impact on behavior,” Hsiao says. The most interesting thing about the results, she says, was not the correction of the autistic symptoms in the mice, but the clues the study provided about how the gut’s microbial population may affect the brain and behavior. The researchers found that levels of a substance called 4-ethylphenylsulfate that is produced by gut bacteria increased 46-fold in the mice with autistic symptoms, but returned to normal after treatment with B. fragilis. When the team isolated that chemical and injected it into healthy mice, the rodents showed increased anxiety, another autismlike symptom, she says. Although the substance did not provoke the symptoms seen in the previous experiment, Hsiao says that the animals’ altered response suggests that the substance could play a role in the disorder. Hundreds of other metabolic byproducts also changed in quantity after B. fragilis was administered and could have an effect, she adds.
By demonstrating that a widely used mouse model of autism does have gastrointestinal problems, and that these problems are associated with behavioral symptoms, the new research “shows us something fabulous,” says Betty Diamond, an immunologist at the Feinstein Institute for Medical Research in Manhasset, New York. She cautions, however, that it would be premature to use B. fragilis or another probiotic as a treatment in humans. “We don’t really understand” which bacterial species are important or how they colonize the gut, she says.
Although the findings are interesting, the study does not establish that the changing levels of microbes and the chemicals they produce caused any of the behavioral changes seen in the mice, says Emanuel DiCicco-Bloom, a neuroscientist at Rutgers University in New Brunswick, New Jersey. “I’d want to know more about the mechanism” by which the bacteria altered behavior in the mice before beginning to translate the findings to humans, he says. The group also didn’t investigate how the bacteria affect a normal animal, because the microbes were administered only to autistic mice, he says. It’s possible that B. fragilis could have a deleterious effect that the study didn’t detect, he says. Combined with the inherent difficulty of extrapolating findings about human autism from a mouse, he says, “I think this is less well-established than it appears.”
“We propose that after the repair of the leaky gut, neurotoxic molecules do not get into the system and cause behavioral abnormalities,” Mazmanian says. But he agrees with DiCicco-Bloom that there are alternative explanations for why the mice changed their behavior—for example, “maybe bacteria are activating nerves in the gut that are communicating with the brain,” he says. After resolving some of these questions, the group plans to initiate clinical trials in humans, Hsiao says. “We don’t want people to start applying this to humans” just yet, but “this opens the door to future research” in people.
Article retrieved from: http://news.sciencemag.org/biology/2013/12/gut-microbes-linked-autismlike-symptoms-mice