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Ginkgo May Reduce PAD Risk December 30, 2009

Posted by Dreamhealer in Alternative medicine.

PITTSBURGH, Pa.—Ginkgo biloba may help reduce peripheral vascular disease (PAD), but showed no evidence it reduced cardiovascular disease (CVD) in a new study from the American Heart Association (CIRCOUTCOMES. 2009 Published online before print November 24, 2009, doi: 10.1161/.109.871640).

The study’s aim was to look at ginkgo and CVD, which was a preplanned secondary outcome of the Ginkgo Evaluation of Memory (GEM) Study, published in November 2008. The GEM trial reported ginkgo had no effect on the incident dementia.

For this new double-blind trial, researchers randomly assigned 3,069 participants older than 75 years of age to 120 mg of Ginkgo biloba twice daily or placebo. After six years, ginkgo supplementation was associated with a reduced risk of PAD. Only 35 PAD events were reported among the subjects; 12 (0.8 percent) in the ginkgo group and 23 (1.5 percent) in the placebo group (P=0.04).

However, ginkgo did not prove to reduce CVD. There were 355 deaths in the study, 87 due to coronary heart disease with no differences between the ginkgo and the placebo groups. There were no differences in incident myocardial infarction (n=164), angina pectoris (n=207) or stroke (151) between the two groups. There were 24 hemorrhagic strokes, 16 in the ginkgo group and eight in the on placebo group; this was not statically significant.


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