DCA shows promise for brain tumour treatment May 21, 2010Posted by Dreamhealer in Alternative medicine, Healing, Research.
TORONTO – A cheap generic drug that caused a big buzz a few years ago when it was found to shrink tumours in laboratory rats may provide a key for treating one of the deadliest cancers in humans, researchers say.
Reporting in the journal Science Translational Medicine on Wednesday, scientists at the University of Alberta say they tested the compound DCA (dichloroacetate) in five people with brain tumours known as glioblastomas.
The drug, which alters the way cancer cells metabolize nutrients to stay alive and keep on multiplying, was found to have positive effects in most of the patients. Brain scans showed tumour growth in four of the patients was arrested after 15 months of treatment. In three, the tumours shrank.
But co-lead investigator Dr. Evangelos Michelakis, a professor of medicine, stressed that much more research on many more patients is needed before any conclusions can be drawn about DCA’s effectiveness in treating glioblastomas.
“This paper was not supposed to announce the results of a trial, this is very few patients,” he said from Edmonton. “The main objective of this paper was to determine what the mechanism of DCA is in humans with glioblastomas, because you cannot extrapolate from animals.” Read More….