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Green Tea and Cancer September 5, 2018

Posted by Dreamhealer in best vancouver naturopath, Cancer, cancer prevention, cancer therapy, Cancer Treatment, Chemotherapy, Healing, integrative cancer care, naturopath, naturopathic, Naturopathic Doctor, Naturopathic Medicine, naturpathic medicine.
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Written By: Dr. Adam McLeod, ND, BSc (Hons)

Green tea is a common beverage that can be found at any cafe yet it also has important therapeutic properties.

Epigallocatechin gallate (EGCG) is an extract from green tea that has shown great promise as an integrative cancer therapy. The mechanism of action is complicated because it interacts with multiple molecular pathways to inhibit the growth of cancerous cells. When cancer cells are exposed to EGCG, it triggers cell death by a variety of mechanisms1,2,3,4. Not only does it inhibit the growth of cancerous cells, but it also slows down the rate of metastasis.

Although there is a wide range of EGCG content in green tea, a strong tea has about 70mg per tea bag. The therapeutic doses for EGCG (particularly in the context of cancer) is a minimum of 1500mg per day. Which means you would have to have approximately 20 green teas per day to reach this dose. Obviously this is not practical as a long term treatment plan so the best way to get the appropriate doses is through pill form. If you enjoy having green tea then you can certainly continue to do so but you will not be significantly contributing to the therapeutic effect of the EGCG.

One important characteristic of EGCG is that it acts as an anti-angiogenic substance. Angiogenesis is the growth of new blood vessels into a developing tumour. This process is necessary when cancer cells are spreading because the smaller growths need a blood supply to sustain their rapid growth. Cancer cells will often secrete chemicals that trick the human body into growing blood vessels into the tumour. EGCG helps to inhibit this process by inhibiting the viability of capillary tube formation and migration. This effect seems to be greatly enhanced by a new class of drugs called ERK inhibitors2.

Tumour samples of mice treated with EGCG clearly show that the cancerous cells have reduced ERK activity while having enhanced p38 and JNK activity. In other words, the pathways that promote growth are down-regulated and the pathways that inhibit growth are up-regulated. The net effect is that the cancer does not grow or spread as quickly. Every molecular marker that was tested indicated that the cancer was less aggressive and more prone to cell death. If you perform a quick Google scholar search, you will see hundreds of well-controlled studies that consistently demonstrate this anti-cancer effect.

When EGCG is combined with curcumin at high doses, it helps to stabilize leukemias and lymphomas. There are many well-documented cases of patients with multiple myeloma who have had long-term disease stabilization by simply taking high doses of EGCG and curcumin. These natural compounds work synergistically to reduce inflammation and promote cell death in cancerous cells. The effectiveness of EGCG in multiple myeloma is undeniable, and this has resulted in a resurgence of research into its use as an adjunctive cancer therapy6.

There are a handful of chemotherapy drugs where the use of EGCG is contraindicated such as bortezomib (Velcade). There is contradictory information about the significance of this interaction, but it is still best to avoid combining EGCG with velcade15. Some doctors focus on this one interaction while ignoring the overwhelming evidence that EGCG often acts synergistically with other forms of chemotherapy. It is difficult to argue against the use of EGCG if you take the time to actually look at the evidence. When EGCG is combined with cisplatin, it not only significantly increases the effectiveness of the drug, it also dramatically reduces the side effect profile7,8,9.

Recently in the media, concerns have been raised about the connection between EGCG and liver toxicity. These liver toxicity reactions that are potentially related to EGCG are exceptionally rare considering how regularly EGCG is consumed in the general population. There have been several documented case studies of liver toxicity that have been connected to use of EGCG. It appears that there may be a genetic predisposition to these rare reactions12. At this point in the time mechanism of action for these reactions is unclear, however, it is in many cases likely due to a immune-allergic mechanism. In other words, it could be that some of these patients were just simply allergic to EGCG.

There is contradictory information regarding the impact of EGCG on liver as several animal studies indicate that it actually has a strong protective effect on the liver and kidneys10. I can tell you from experience that I have literally prescribed EGCG thousands of times and I have never seen even a hint of such reaction. EGCG is a exceptionally safe supplement when used appropriately and patients should not be fearful of using it due to a handful of exceptionally rare cases of liver toxicity.

EGCG is an example of a supplement where the quality makes a significant difference. In order to obtain the desired anti-cancer effect, you must take high doses of quality EGCG. Drinking green tea may be helpful in the context of cancer prevention, but when it comes to cancer treatment, you need much higher doses. Some physicians recommend that patients get EGCG administered by intravenous therapy to get the doses as high as possible. The doses required to enhance chemotherapy and promote cell death in cancerous cells are quite high, but they are obtainable by consuming EGCG orally. It is also important to point out that this treatment is cost effective and generally well tolerated by patients.

Dr. Adam McLeod is a Naturopathic Doctor (ND), BSc. (Hon) Molecular biology, Motivational Speaker and International Best Selling Author. He currently practices at his clinic in Vancouver, British Columbia where he focuses on integrative cancer care, providing the best care in integrative oncology. http://www.yaletownnaturopathic.com

Dr. McLeod will be holding two seminars in 2018, Vancouver, British Columbia and Toronto, Ontario. For more information on his seminars please visit the website: http://www.dreamhealer.com/workshop/

References:

1) Ahmad, Nihal, Sanjay Gupta, and Hasan Mukhtar. “Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κB in cancer cells versus normal cells.” Archives of biochemistry and biophysics 376.2 (2000): 338-346.

2) Shankar, Sharmila, et al. “EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer.” Frontiers in bioscience: a journal and virtual library 13 (2007): 440-452.

3) Hwang, Jin-Taek, et al. “Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway.” Cancer letters 247.1 (2007): 115-121.

4) Shimizu, Masahito, et al. “EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.” Journal of experimental therapeutics & oncology 5.1 (2004): 69-78.

5) Shah, Jatin J., Deborah J. Kuhn, and Robert Z. Orlowski. “Bortezomib and EGCG: no green tea for you?.” Blood 113.23 (2009): 5695-5696.

6) Shammas, Masood A., et al. “Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications.” Blood 108.8 (2006): 2804-2810.

7) El-Mowafy, A. M., et al. “Novel chemotherapeutic and renal protective effects for the green tea (EGCG): role of oxidative stress and inflammatory-cytokine signaling.” Phytomedicine 17.14 (2010): 1067-1075.

8) Davenport, Andrew, et al. “Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells.” International journal of molecular medicine 25.3 (2010): 465-470.

9) Sarkar, Fazlul H., and Yiwei Li. “Using chemopreventive agents to enhance the efficacy of cancer therapy.” Cancer Research 66.7 (2006): 3347-3350.

10) Niu, Yucun, et al. “The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age‐associated inflammation and oxidative stress in healthy rats.” Aging Cell 12.6 (2013): 1041-1049.

11) Chen, Ju-Hua, et al. “Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide–derived prooxidants.” The American journal of clinical nutrition 80.3 (2004): 742-751.

12) Church, Rachel J., et al. “Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice.” Food and Chemical Toxicology 76 (2015): 19-26.

DCA and Cancer August 27, 2014

Posted by Dreamhealer in Alternative medicine, Cancer, Chemotherapy, Integrative Medicine, naturopathic, Naturopathic Medicine, Research.
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DCA and it's use in integrative oncology

DCA and it’s use in integrative oncology

By: Dr. Adam McLeod , ND, BSc

Several years ago there was a huge buzz in the media about Dichloroacetic Acid (DCA) and its use in cancer1. The public was outraged that DCA could be an effective cancer therapy and that the government showed little interest because DCA could not be patented. The drug companies ignored any evidence related to this therapy because without a patent it was simply not a profitable venture. Fortunately, some private researchers raised enough money to continue studies into this simple yet effective therapy.

DCA was initially used for lactic acidosis, a condition where the blood has high levels of lactic acid. The DCA inhibits the enzyme pyruvate dehydrogenase kinase which causes a major shift in metabolism from fermentation to oxidation in the mitochondria2. In other words, it forces the mitochondria in cells to become more active. This is relevant to cancer because the survival of cancer cells depends on the mitochondria being dormant. The mitochondria are capable of triggering cell death in abnormal or damaged cells. Cancer cells are grossly abnormal and they often depend on the mitochondria being inactive.

The ultimate goal of this therapy is to activate the mitochondria and allow them to trigger cell death in the abnormal cancerous cells. The DCA will certainly help to activate these pathways but it is essential that patients also exercise. By regularly doing aerobic exercise you are also stimulating the mitochondria. The excessive energetic demands during exercise trigger the mitochondria to be more active and burn oxygen. DCA when combined with exercise significantly increases the consumption of oxygen by the mitochondria which is an indication that the mitochondria are being further activated5.

It is essential for cancer patients (not just patients on DCA) to do aerobic exercise if they are physically able to. It does not matter what that type of exercise it is, just as long as it is a moderate aerobic exercise that you are able to do on a regular basis. There is an overwhelming body of evidence which clearly shows that cancer patients who regularly exercise simply do much better than those who do not. It is possible that this mitochondrial activation could be one of the reasons for this.

Most of the research seems to indicate that DCA is more effective for cancers that are localized in the nervous system3. Although it can be used for other types of cancer, it is less indicated for cancers that do not localize to the nervous system. A very common side effect from chemotherapy is neuropathy4 and DCA should be used with caution if there are any signs of neuropathy. There are no known drug interactions with DCA except for the drug Lasix which is a diuretic. Overall DCA is a very safe therapy and there are many studies that demonstrate the safety of this therapy.

The bottom line is that DCA is an effective therapy when used appropriately. It is not a cure on its own but DCA can be a major part of an effective and comprehensive integrative cancer treatment plan. It can be administered either orally or intravenously. The oral dose is typically 15-20mg/kg and it is cycled 2 weeks on followed by 1 week off. It is extremely important to have the appropriate neurological support during this therapy. DCA is known to cause significant neuropathy and you must be monitored by a physician who is experienced with the use of DCA. Common neurological support includes NAC, Thiamine (B1) and ALA. It is essential that you consult with a Naturopathic physician who focuses in oncology to know what neurological support is best suited for you.

A Naturopathic doctor that works with oncology will take the time to look at your case and will write you a prescription for DCA if it is truly indicated. Contact Yaletown Naturopathic Clinic to see if this is the right therapy for you.

Dr. Adam McLeod is a Naturopathic Doctor (ND), BSc. (Hon) Molecular biology, First Nations Healer, Motivational Speaker and International Best Selling Author. He currently practices at his clinic in Vancouver, British Columbia where he focuses on integrative oncology. http://www.yaletownnaturopathic.com

References

1) “Cheap, ‘safe’ drug kills most cancers”. New Scientist. 2007-01-17. Retrieved 2014-08-23.

2) Stacpoole PW (1989). “The pharmacology of dichloroacetate”. Metabolism 38 (11): 1124–1144. doi:10.1016/0026-0495(89)90051-6PMID 2554095

3) Michelakis E D, et al. Metabolic Modulation of Glioblastoma with Dichloriacetate. Sci Transl Med 12 May 2010: Vol. 2, Issue 31

4) Abramowski MC. Chemotherapy-Induced Neuropathic Pain. J of the Advanced Practitioner in Oncology. 2010;1:279-283.

5) Ludvik, Bernhard, et al. “Effects of dichloroacetate on exercise performance in healthy volunteers.” Pflügers Archiv 423.3-4 (1993): 251-254.

Heat: The Achilles Heel of Cancer June 2, 2014

Posted by Dreamhealer in Alternative medicine, Cancer, Dreamhealer, Healing, Health, Integrative Medicine, naturopathic, Naturopathic Medicine, Naturopathy, Prostate Cancer, Research.
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Heat: The Achilles Heel of Cancer

Written By: Dr. Adam McLeod, ND

It is a well established fact that cancer cells are vulnerable to heat1,2. On a cellular level it makes intuitive sense that cancer cells would be sensitive to heat. Normal cells are spatially arranged so that heat can be distributed evenly and they will not divide if they are physically in contact with adjacent cells. Cancer cells within a tumour will continue to divide regardless of the proximity of adjacent cells; this is one of the hallmarks of cancer. As a result of this uncontrolled growth, the cells in the tumour become densely packed together and this makes it very difficult for them to effectively distribute heat.

Hyperthermia treatment is rapidly becoming a mainstream therapy for patients undergoing chemotherapy and radiation. During these treatments the patients’ core body temperature is artificially raised to mimic a strong fever. This is not a pleasant experience for the patient but it is very effective at weakening the cancer cells. It makes these cancer cells more vulnerable to chemotherapy and radiation.

When any cell is exposed to heat there are immediate biochemical and genetic changes that occur so that the cell can adapt to the new warm environment. One of the most potent responses that allows these cells to survive the heat is the production of heat shock proteins (HSP)3. These HSPs protect components within the cell that are vulnerable to heat damage and during hyperthermia the production of these proteins within cancer cells is what allows them to survive. Currently there is a major push with pharmaceutical companies to develop drugs that inhibit these proteins.

There are several different natural compounds which are well documented heat shock protein inhibitors. These substances are safe when used in the right clinical context and you need to consult a Naturopathic Doctor to know if this is the best therapy for that specific type of cancer. One example is Quercetin, a bioflavonoid that is well documented as a potent inhibitor of heat shock proteins in cancer cells4,5,6,7,8,9.

Cancer cells are naturally very vulnerable to heat based on how densely the cells are packed together. When hyperthermia is combined with Quercetin the results are very dramatic10. In one study on prostate carcinoma they concluded that, “When combined in a treatment protocol with hyperthermia, Quercetin drastically inhibited tumour growth and potently amplified the effects of hyperthermia on two prostate tumour types, PC-3 and DU-145 in vivo. These experiments, thus, suggest the use of Quercetin as a hyperthermia sensitizer in the treatment of prostate carcinoma.”

It is extremely important to point out two things. Firstly, Quercetin is safe with most but not all chemotherapy drugs and you need professional guidance from a Naturopathic Doctor who focuses in oncology to know if this is safe for you. Secondly, the quality of the Quercetin supplement makes a big difference. Generally speaking Quercetin is very poorly absorbed and there are only a few professional brands of sufficient quality that are effective at sensitizing the cancer cells. In some cases, intravenous Quercetin is more appropriate.

The mainstream medical community is changing its tune with regards to hyperthermia. In private hospitals in the United States it is very commonly used because it is so effective. In Canada, there are only a handful of clinics that currently offer this therapy. As the evidence for this therapy accumulates, in the near future hyperthermia combined with these natural approaches will undoubtedly become the standard of care for cancer patients.

 

Dr. Adam McLeod is a Naturopathic Doctor (ND), BSc. (Hon) Molecular biology, First Nations Healer, Motivational Speaker and International Best Selling Author. He currently practices at his clinic in Vancouver, British Columbia where he focuses on integrative oncology. http://www.yaletownnaturopathic.com

References:

1. Van der Zee J. Heating the patient: a promising approach? Ann Oncol, 2002. 13(8): p. 1173-84.

2. Van der Zee J and MC Erasmus. Hyperthermia in addition to radiotherapy. Clin Oncol (R Coll Radiol), 2007. 19(3 Suppl): S18.

3. De Maio A (January 1999). “Heat shock proteins: facts, thoughts, and dreams”. Shock (Augusta, Ga.) 11 (1):1-12.

4.  Hansen, R. K., et al. “Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells.” Biochemical and biophysical research communications 239.3 (1997): 851-856.

5. Gonzalez, Oscar, et al. “The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production.” Hepatology 50.6 (2009): 1756-1764.

6. Wei, Yu-quan, et al. “Induction of apoptosis by quercetin: involvement of heat shock protein.” Cancer Research 54.18 (1994): 4952-4957.

7. Zanini, Cristina, et al. “Inhibition of heat shock proteins (HSP) expression by quercetin and differential doxorubicin sensitization in neuroblastoma and Ewing’s sarcoma cell lines.” Journal of neurochemistry 103.4 (2007): 1344-1354.

8. Hosokawa, Nobuko, et al. “Flavonoids inhibit the expression of heat shock proteins.” Cell structure and function 15.6 (1990): 393-401.

9. Elia, Guiliano, and M. G. Santoro. “Regulation of heat shock protein synthesis by quercetin in human erythroleukaemia cells.” Biochem. J 300 (1994): 201-209.

10. Asea, A., et al. “Effects of the flavonoid drug quercetin on the response of human prostate tumours to hyperthermia in vitro and in vivo.” International journal of hyperthermia 17.4 (2001): 347-356.

 

Bacteria help kids stay healthy! March 30, 2014

Posted by Dreamhealer in Allergies, Alternative medicine, Antibiotics, Colds, Diet, Dreamhealer, Experiments, Healing, Health, Integrative Medicine, naturopathic, Naturopathic Medicine, Naturopathy, Research, Skeptics.
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By: Drs. Kay Judge and Maxine Barish-Wreden

Breaking news: Bacteria help kids stay healthy! In a study published this month in the Journal of Pediatrics, scientist found that daily probiotics help toddlers avoid certain infections. Researchers enrolled 300 children, ages 6 months to 36 months, in day care centers in a double-blinded study. Half of the children received placebos and half received probiotics.

For the children who received probiotics, it was found that there was a reduction in frequency and duration of diarrhea episodes. And surprisingly, there was also a reduction in respiratory tract infections in the children who took probiotics.

The children in the study received the probiotic Lactobaccillus reuteri daily for three months. In addition to the already-mentioned health benefits, the study found a reduction in the number of doctor visits, antibiotic use, absenteeism from day school and parental absenteeism from work.

Other studies on probiotics have found that probiotics may help in reducing acute diarrhea, antibiotic-associated diarrhea, atopic eczema, tooth decay, C. diff. bacteria colitis, irritable bowel syndrome and inflammatory bowel disease, including pouchitis.

So what is this miracle drug? Probiotics are live microorganisms numbering over 100 trillion, including over 500 bacterial species, which normally reside in the human intestinal tract. These microorganisms help in digestion, provide the body with nutrients, help the immune system and help keep harmful microorganisms in check.

Common probiotics are Lactobacillus bulgaris, Streptococcus thermophiles, Lactobacillus acidophilus and casei, and Bifidobacteria. One can maintain a healthy balance of these “good bacteria” in the body by taking products which contain live and active cultures of these bacteria. These can include the pill and liquid probiotic supplements, as well as foods such as yogurt, and fermented foods such as brewer’s yeast, miso, sauerkraut or micro algae.

If you need additional nondairy yogurt options, yogurts made from rice, soy and coconut milk are available on the market. Some of these can contain added probiotics that provide the same benefits as regular yogurt. To ensure that you are getting the benefit of the probiotics in the foods that you are eating, pick those that state “live and active cultures” on the label. Also look for supplements that are not close to their expiration date, as the live bacteria dwindle over time.

Retrieved from: http://www.ledger-enquirer.com/2014/03/28/3027893/integrative-medicine-probiotics.html

For more information about alternative medicine check out http://www.dreamhealer.com

Gut Microbes Linked to Autism-like Symptoms in Mice December 6, 2013

Posted by Dreamhealer in ADHD, Allergies, Alternative medicine, Antibiotics, Experiments, Genetics, Healing, Health, naturopathic, Naturopathic Medicine, Naturopathy, Research.
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By: Emily Underwood

Many physicians and parents report that their autistic children have unusually severe gastrointestinal problems, such as chronic constipation or diarrhea. These observations have led some researchers to speculate that an ailing gut contributes to the disorder in some cases, but scientific data has been lacking. Now, a provocative study claims that a probiotic treatment for gastrointestinal issues can reduce autismlike symptoms in mice and suggests that this treatment could work for humans, too.

The reported incidence of gut maladies in people with autism varies wildly between published studies—from zero to more than 80%—making it difficult to establish just how commonly the two conditions go together, says principal investigator Sarkis Mazmanian, a microbiologist at the California Institute of Technology (Caltech) in Pasadena. Overall, however, the evidence seems to point toward a connection. Last year, for example, a Centers for Disease Control and Prevention study of thousands of children with developmental disabilities found that kids with autism were twice as likely as children with other types of disorders to have frequent diarrhea or colitis, an inflammation of the large intestine.

For many years, Mazmanian and his and colleagues have been studying the effects of a nontoxic strain of the bacterium Bacteroides fragilis on diseases such as Crohn’s disease, which causes intestinal inflammation and allows potentially harmful substances that should pass out of the body to leak through junctions between cells that are normally tight. Although the researchers don’t understand the mechanism, the bacterium appears to restore the damaged gut, possibly by helping close these gaps.

“The fact that we have an organism that repairs the gut makes it a very appealing” tool for testing whether gut abnormalities can contribute to autism, Mazmanian says. To explore that question, Mazmanian and colleagues at Caltech used a mouse model of autism that is thought to approximately recreate three of the disorder’s hallmark deficits: lack of social interaction, decreased communication (mice normally emit ultrasonic, birdsonglike chirps), and repetitive behaviors such as compulsive grooming or burying marbles.

The first step of the experiment was to determine whether the mice showed signs of gastrointestinal inflammation or other gut abnormalities, says microbiologist Elaine Hsiao, a postdoctoral candidate at Caltech and lead author of the study. By the time the mice were 3 weeks old, the researchers found that their intestines were indeed as leaky as those of mice that had been treated with a chemical that induces colitis. Next, the researchers tested whether they could reverse the damage by feeding the mice applesauce laced with B. fragilis for a week. A second group of autism-mimicking mice as well as a group of healthy mice ate applesauce that did not contain the bacteria. Then the group waited to see what effect the bacteria would have on the rodents’ intestines. “We didn’t know what would happen—we were hoping the bacterium would survive in the gut,” Hsiao says.

After 3 weeks, the team measured the levels of gut-derived molecules in the rodents’ bloodstream and found that the treatment had stopped up their intestinal leakage. Bacterial counts from rodents’ poop showed that although B. fragilis did not establish lasting colonies in the mice, they did “shake up the community,” of microorganisms, bringing it closer to that of the normal mice, Hsiao says. After the treatment, the autism-mimicking mice also resembled their normal peers in two behavioral tests, the authors report today in Cell. The animals no longer compulsively buried marbles in their cages and increased their ultrasonic squeaking to typical levels. They did not increase their social interactions, however, Hsiao says.

“It’s really striking that any bacterial treatment—even a transient one—could have a lasting impact on behavior,” Hsiao says. The most interesting thing about the results, she says, was not the correction of the autistic symptoms in the mice, but the clues the study provided about how the gut’s microbial population may affect the brain and behavior. The researchers found that levels of a substance called 4-ethylphenylsulfate that is produced by gut bacteria increased 46-fold in the mice with autistic symptoms, but returned to normal after treatment with B. fragilis. When the team isolated that chemical and injected it into healthy mice, the rodents showed increased anxiety, another autismlike symptom, she says. Although the substance did not provoke the symptoms seen in the previous experiment, Hsiao says that the animals’ altered response suggests that the substance could play a role in the disorder. Hundreds of other metabolic byproducts also changed in quantity after B. fragilis was administered and could have an effect, she adds.

By demonstrating that a widely used mouse model of autism does have gastrointestinal problems, and that these problems are associated with behavioral symptoms, the new research “shows us something fabulous,” says Betty Diamond, an immunologist at the Feinstein Institute for Medical Research in Manhasset, New York. She cautions, however, that it would be premature to use B. fragilis or another probiotic as a treatment in humans. “We don’t really understand” which bacterial species are important or how they colonize the gut, she says.

Although the findings are interesting, the study does not establish that the changing levels of microbes and the chemicals they produce caused any of the behavioral changes seen in the mice, says Emanuel DiCicco-Bloom, a neuroscientist at Rutgers University in New Brunswick, New Jersey. “I’d want to know more about the mechanism” by which the bacteria altered behavior in the mice before beginning to translate the findings to humans, he says. The group also didn’t investigate how the bacteria affect a normal animal, because the microbes were administered only to autistic mice, he says. It’s possible that B. fragilis could have a deleterious effect that the study didn’t detect, he says. Combined with the inherent difficulty of extrapolating findings about human autism from a mouse, he says, “I think this is less well-established than it appears.”

“We propose that after the repair of the leaky gut, neurotoxic molecules do not get into the system and cause behavioral abnormalities,” Mazmanian says. But he agrees with DiCicco-Bloom that there are alternative explanations for why the mice changed their behavior—for example, “maybe bacteria are activating nerves in the gut that are communicating with the brain,” he says. After resolving some of these questions, the group plans to initiate clinical trials in humans, Hsiao says. “We don’t want people to start applying this to humans” just yet, but “this opens the door to future research” in people.

Article retrieved from: http://news.sciencemag.org/biology/2013/12/gut-microbes-linked-autismlike-symptoms-mice

You’re What Kind of Doctor? July 20, 2013

Posted by Dreamhealer in Alternative medicine, Dreamhealer, exercise, Experiments, Healing, Integrative Medicine, naturopathic, Naturopathic Medicine, Naturopathy.
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Article written by Dr. Michael Stanclift, N.D.

“Wait, you’re what kind of doctor? A nat-uro-pathic doctor? What’s that?”

I get this question all the time. It’s not so surprising when it comes from someone I meet in a coffee shop or on an airplane, but I still hear it from other doctors, too. In fact, it’s more surprising when someone (outside of Seattle or Portland) has actually heard of what I do. To be fair, I’d never heard of an audiologist until one moved in as a housemate.

My profession is rather small, and we’re yet to be licensed in every state. Naturopathic doctors (NDs) are currently licensed to practice as medical professionals in 16 states, and two U.S. territories, and five provinces in Canada.

What we do probably wouldn’t make for a popular TV show like House or Grey’s Anatomy. Preventing heart disease and cancer through diet or helping someone break the pattern of insomnia is not nearly as exciting as rare diagnoses or ethically questionable emergency transplant surgeries. In fact, when some “alternative” health approach is portrayed on one of these shows, you can be fairly certain it’s why the patient is so ill. Ironic, considering the now-famous JAMA article reporting “medical treatment” as a leading cause of death in the United States.

When I say “naturopathic doctor,” to some folks it conjures up ideas of magic wands, potions, and Kramer’s holistic healer friend on Seinfeld. These sorts of clips (though hilarious!) highlight the misconceptions around what we do. Hopefully this article will help clarify what kind of training an ND gets and what they can do.

Licensed Naturopathic Doctors Have Scientific Medical Training:

Applicants to accredited naturopathic medical colleges need a bachelor’s degree and a competitive GPA in scientific prerequisites, just like applicants to “conventional” medical schools.

After admission, the course work of the first two years of naturopathic and “conventional” medical school is comparable both in subjects and in hours of training. We learn all the basic medical sciences like anatomy, pathology, and biochemistry. Unlike Kramer’s holistic healing friend, we learn to use the same labs, physical exams, and medical imaging (X-ray, CT, MRI) that hospitals and clinics utilize to diagnose diseases and monitor health. It’s pretty rare for me to have to break out the magic wand or have someone drink a cup of tea while wearing the pyramid hat!

Our clinical training is a bit different from “conventional” medical clerkships. As ND students, we spend all our clinical time in a family practice (outpatient) setting, under the supervision of an attending (usually ND) physician. Our training includes minor surgery, like removing a mole, but we don’t go into the major surgeries that happen in hospitals. Instead of rotating through a variety of medical specialties, we learn when and how to refer to specialists to diagnose or treat conditions beyond our scope, just like any other family doctor. There are few residencies available for NDs, and since all of our clinical time is spent in family medicine, we tend to go straight into private practice with other medical providers.

Depending on the state, our naturopathic medical license covers everything from dietary advice to pharmaceuticals and suturing wounds. For instance, in California my license is nearly identical to that of a nurse practitioner or physician’s assistant. In Washington and Oregon, the license covers a greater scope of practices and ND care is covered by nearly every insurance provider. Unfortunately, health insurance doesn’t cover ND services in every state we’re licensed to practice in, but our professional organization, the AANP, is working to change that.

Naturopathic Medicine Is Not the Same Thing as Homeopathy

Homeopathy means to give a medicine in a very small dose. Scientifically, we don’t know why it works, because the doses are so small. Naturopathic medicine is not how medicine is given specifically, but based on our six principles. Naturopathic medicine refers to an approach to treating people, and tends to favor natural and low-force interventions. Our treatments with patients might include dietary changes, supplementary nutrients, exercise, herbal medicine, pharmaceuticals or homeopathy. So homeopathy can be part of an ND’s treatment plan, but it’s not the only tool in the shed. That said, other medical providers may use homeopathy as well, and it doesn’t make them naturopathic doctors.

Naturopathic Doctors Work Alongside Medical Doctors

Some folks assume that NDs are against “conventional” medicine, but this isn’t true. Health care is best provided by a team, and NDs are only one part of the team. There are times when we shine, and times when specialists or other medical providers are best suited for the task at hand. We refer our patients to surgeons, cardiologists, and ERs when it’s clear their conditions are beyond of our scope of training.

Naturopathic Doctors and “Naturopaths” Are Different Things

This is probably one of the most confusing things in our field. Even in a state like California, where NDs are licensed as medical providers and the term “naturopathic doctor” is protected by law, people with questionable training can call themselves “naturopaths.” Someone operating as a “naturopath” can see clients as long as they don’t “practice medicine.” Luckily for patients, there are national and state professional associations for NDs, and departments in each state to check whether someone you’d like to see has passed their board exams and has a current license. Not every licensed ND will be a member of their professional organization (like me, since I live outside the U.S.), but they are a good place to start when looking for someone in your area.

Another thing patients need to look out for are people who advertise themselves as an ND (or NMD) without having a license. I’ve reported several people like this to California’s Naturopathic Medicine Committee in the last year. So the moral of the story is, check to see that your health care providers have current licenses issued by the state (they should also be displayed for you to see in their office).

What Makes Naturopathic Doctors Different

Our patients often tell us the face-to-face time we spend with them is a lot longer than other doctors they’ve seen. We spend that time getting to know each patient as a person. We ask about everything that’s going on with them physically, emotionally, and oftentimes spiritually. When making a specific recommendation or prescription, we spend time explaining treatment options and answering questions. We aim to teach our patients about their health, and how they can care for it.

Our treatments are advised using the therapeutic order, where we start by laying the basic foundations for healthy living, and use higher-force interventions (like specific nutrients, drugs and surgeries) as conditions become more severe. In this way, we also work with patients who haven’t developed a disease yet, and simply seek to improve their health whether it be physically, emotionally or spiritually. We consider the term “health care” from its true meaning.

We know our patients are literally atoms, molecules, cells and organs, but we appreciate that they are so much more those physical components. We each exist uniquely in the world, with different values and priorities, and as NDs we believe our health care should reflect that.

So yeah, some of us are a little “out there,” and “touchy-feely.” But that’s not all that guides our practice. Remember, naturopathic doctors go to real medical school. We take realboard exams. Our “hippie” medicine works, and what we do is becoming less “alternative” and more “conventional” everyday.

Link to original article.

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Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial June 27, 2013

Posted by Dreamhealer in Alternative medicine, Cardiovascular disease, Dreamhealer, exercise, Healing, Health, Healthcare, Heart, Medication, naturopathic.
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Here is a recent randomized clinical trial that clearly demonstrated Naturopathic medicine can significantly reduce the risk of cardiovascular disease.

Abstract:

Although cardiovascular disease may be partially preventable through dietary and lifestyle-based interventions, few individuals at risk receive intensive dietary and lifestyle counselling. We performed a randomized controlled trial to evaluate the effectiveness of naturopathic care in reducing the risk of cardiovascular disease.

Results:

Of 246 participants randomly assigned to a study group, 207 completed the study. The characteristics of participants in both groups were similar at baseline. Compared with participants in the control group, at 52 weeks those in the naturopathic group had a reduced adjusted 10-year cardiovascular risk (control: 10.81%; naturopathic group: 7.74%; risk reduction −3.07% [95% confidence interval (CI) −4.35% to −1.78%], p < 0.001) and a lower adjusted frequency of metabolic syndrome (control group: 48.48%; naturopathic care: 31.58%; risk reduction −16.90% [95% CI −29.55% to −4.25%], p = 0.002). Our findings support the hypothesis that the addition of naturopathic care to enhanced usual care may reduce the risk of cardiovascular disease among those at high risk.

For those of you who wish to read the entire peer reviewed article, here is a direct link to the study:

Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial

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Intention Heals February 7, 2013

Posted by Dreamhealer in Alternative medicine, Books, Dreamhealer, Energy Healing, exercise, Healing, Health, Integrative Medicine, Meditation, naturopathic.
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Our thoughts are energy. Intention is focused thought which affects all physical matter. Once you decide to take control of your mind which in turn regulates your body, then you will be in control.

My studies in University have shown me what science is beginning to discover about the biological and chemical correlates of our thoughts and intentions. The carrier or dynamic at work is energy. The beauty of self-empowerment is that you are making this discovery yourself, as you learn to activate and maximize your own innate energy abilities to create your reality of health and well-being.
Taken from my fourth book Intention Heals.
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Focus Your Mind on Healing January 17, 2013

Posted by Dreamhealer in Alternative medicine, Dreamhealer, Energy Healing, Healing, Health, Integrative Medicine, Meditation, naturopathic, Spirituality.
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Visualization is a tool to help you take control of your own intentions. This can help you to align your conscious and subconscious mind in a way that is optimal for healing. Visualizations accelerate the healing process by getting all of your cells working together towards optimal health.

Use whatever your most dominant sense is to your advantage when visualizing. Some people are more tuned into auditory memory and they prefer to visualize healing music. Others remember visual stimuli and prefer to visualize dynamic healing images. Ideally we want to visualize using all of our senses and this comes with practice.

Your subconscious acts as a filter, bringing details to your conscious awareness on a need-to -know basis as there is so much information streaming at you constantly. What you are aware of is what you focus on. This can prevent you from seeing the bigger picture. Our reality is what we focus on and what we perceive it to be.

Your brain cannot distinguish between a real event and a perceived event. In other words, your body responds to your mental stimuli the same way as physical stimuli. By making your visualizations as realistic as possible with clear positive intention, you will achieve optimal results. You are recreating yourself in your new experience of wellness. Create your new healthy reality now. Remember that the energy of your intentions is actually being processed as new information within your body. That is the true power of visualization.

The mental imprint from visualizations triggers changes in the neurons of your brain. Neuron connections are strengthened by repeated visualizations. Set what you desire in your conscious mind, and then let your subconscious mind recreate what your intentions are. For example, if you have a headache, your intention is to become pain free. A visualization would be much more specific, sending step- by -step instructions to your body as to how this should be accomplished.

Visualize the blood vessels in the area of pain opening and allowing unrestricted blood flow. Then visualize calming ripples of energy emanating from the area. Imagine every muscle in that area being totally relaxed. Through your focused intentions you can speed up your own healing process.

Simplify your visualization by choosing only one goal before proceeding with any other issues you may have. Prioritizing your goals will help you to determine your focus. Be as concise and specific as possible as you focus your mind on healing.

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The Healing Influence of Your Intentions January 8, 2013

Posted by Dreamhealer in Alternative medicine, Alternatives, Dreamhealer, Energy Healing, exercise, Healing, Health, Integrative Medicine, Meditation, naturopathic.
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Recent findings in molecular biology show that your own intentions directly affect your health by their powerful influence on your metabolism.

So how can you use this knowledge to your advantage? The first step is to recognize your desire for change. Your mind and body will recognize whether or not you are ready and willing to make changes. If you truly are ready, your cells will interpret your intentions to heal as genuine. If your intentions are not sincere they will be viewed and dismissed by your body as background noise.

If you are attempting to feed yourself the same old unproductive thought patterns and just sugarcoat them, think again. For instance, if you are telling yourself that in spring you will start an exercise program, what you are really saying is that these changes are not important enough for you to start now. You are attempting to fool your own cells, and that will never work. They are too smart for that. Who knows you better than yourself? You can’t fool yourself, but you can change yourself.

What is most amazing about your brain is its adaptability. It conforms to your own thought processes through expectations, and is always rebuilding, repairing, and thereby recreating itself. A thought is translated in your brain and your body reacts to that thought. What you think is what you get.

Understand how your environment influences you. Become proactive in how you interpret events, as how you are influenced is up to you. Your perception of this influence is ultimately what affects you, rather than the events themselves. It is important to take in only information that is helpful to you in your healing.

Your sincere intention must be your singular focus. Become self-reflective and totally honest. Focus on how you think, understanding how each thought flows into another thought, and how your thoughts interact with one another. Intention helps to align your conscious awareness with your subconscious thoughts and beliefs. This makes it possible to get every cell working more effectively towards the same goal of health and healing. Your conscious intention must be synchronized, or aligned with your subconscious intention.

Ask yourself, “What do I want?” If your answer is that you want to be healthy, say it aloud. Shout, “I want to be healthy!” Let it resonate within you that this is your intention. This is what you expect. Focus on the expectation that this will happen. Your perception of outcome makes a huge difference. Change any habits or patterns that are not in synchronicity with your healing program. Absorb only information that is helpful to you. Let yourself know that you are seriously focused on the path toward change. Then use your own intentions to give you that extra edge in your healing.

Article retrieved from Examinerhttp://www.examiner.com/article/the-healing-influence-of-your-intentions

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